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diagnosis hematology arteritis bullous cop cryptogenic dermatology differential differentiation gca giantcell hemeonc hemophagocytic hlh lymphohistiocytosis myelitis neurology oncology organizing pemphigoid
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... #diagnosis #management ... #hematology #oncology
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... epidermis from dermis Clinical ... Signs/Symptoms/ ... High-potency topical steroids
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... required +/- prompt ophthalmology ... GCA #Temporal #Signs ... #Management
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... /SYMPTOMS: • Acute ... DIAGNOSTICS: Clinical ... Pneumonia #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Bilateral signs ... and/or symptoms ... Myelitis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Clinical Presentation ... • Common Signs ... and Symptoms: ... Pathophysiology ... #Hematology #HemeOnc
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