21 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... #Binding #KBinders ... Kayexelate #Comparison #Table ... #Pharmacology # ... #HyperKalemia #Nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... #summary #table ... #nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Deep coma (any cause ... stroke, Delayed finding ... differential #diagnosis #table ... #neurology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... works by directly binding ... intracellular calcium causes ... #Pathophysiology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... cyclosilicate #Potassium ... Hyperkalemia #treatment #pharmacology ... #table #comparison ... #nephrology
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
hypothesized from the findings ... be the primary cause ... - Cytokines #Pathophysiology ... #Nephrology #CKD
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Table 22 provides the characteristics of various phosphate-binding agents.
#Pharmacology #Nephrology #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages
Table 22 provides ... various phosphate-binding ... #Pharmacology #Nephrology ... Binders #Comparison #Table
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
require phosphate binding ... since they are not able ... Only* #CKD #Nephrology ... #Dose #Dosing #Pharmacology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Piretanide Potassium ... #Diuretics #Pharmacology ... #nephrology #conversion ... loop #thiazide #classes