10 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology ... HepC #HepatitisC #Management ... #Pharmacology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Hepatitis (AAH) Drug-Induced ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #management #algorithm ... #pharmacology # ... treatment #medications ... decisionaid #cardiology #hematology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
First Line Treatment ... with Preserved Liver ... #Management #Hepatology ... Gastroenterology #oncology ... #Pharmacology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... (A) Suggested treatment ... §Assess drug-drug ... Anticoagulation #Management ... #Hematology #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Cytotoxic drugs ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
) • Sepsis • Drug-induced ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology