29 results
diagnosis management hematology differential neurology anemia barre classification guillain leukemia lupus sle agglutinin aplastic apml arterial arteritis autoimmune blood chronic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... count ↑ PLT • ↑ PBS ... • Tumor lysis syndrome ... ) CLL Symptoms: ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Lymphocytosis on CBC ... diagnosis #workup #oncology ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... count cause hyperviscosity ... >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
pain hematuria syndrome ... hematuria • Signs ... of GN or vasculitis ... necrosis (Sickle cell ... #urology #nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... • Induce blast cell ... Diagnosis: >3 symptoms ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Presentation - Systemic Symptoms ... purpura: strong sign ... Lab Tests: • CBC ... differential #diagnosis #rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
periumbilical region), nausea ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
commonly hairy-cell ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... +Organomegaly+↑RBC ... Autoimmunity: • -MM/WM: Vasculitis ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... Causes: - Idiopathic ... Leukocytoclastic vasculitis ... #dermatology #oncology
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