48 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Examination: • Skin ... but elevated as disease ... , IgG4 related disease ... #cholangitis #diagnosis ... #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Primary biliary Cholangitis ... (PBC) - Other ... Differential #Diagnosis #Algorithm ... #hepatology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Red Blood Cell (RBC ... and Associated Diseases ... Morphologies #Key #Atlas #Microscopy ... #Pathology #Hematology ... Pathologic Basis of Disease
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... infection • Lyme disease ... migrans • Lyme disease ... differential #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... pericarditis • Hepatic: PBC ... primary biliary cholangitis ... interstitial lung disease ... Scleroderma #SSc #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... disorders • Celiac disease ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Algorithm for Diagnosis of the Vesiculobullous Rash

Febrile, Diffuse Distribution:
 - Varicella,  Smallpox,  Disseminated, Gonococcal,
Algorithm for Diagnosis ... Vesiculobullous Rash ... Hand Foot & Mouth Disease ... #Algorithm #Diagnosis ... #Dermatology #Skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... Polyarteritis nodosa • Microscopic ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Onset Still's Disease ... weeks - Typical skin ... rash: maculopapular ... non-pruritic, salmon-pink rash ... #Major #Minor #Rheumatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Target Cell RBC ... differential #diagnosis #hematology ... #microscopy #atlas