19 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... PURPURA: Platelet ... #Differential # ... Diagnosis #hematology
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... - Differential ... Diagnosis Disruption ... collagen vascular disorders ... Thrombocytopenia, Platelet
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... considered first-line ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Nail diseases and disorders.
 - Spoon Nails (Koilonychia)
 - Pitting of Nails
 - Beau's Lines
 -
Nails - Beau's Lines ... white spots) #Diagnosis ... #Differential # ... #Leukonychia #Table ... #Clinical #PhysicalExam
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential ... Diagnosis and Workup ... #Disorders #Differential ... #Diagnosis #Causes
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
without platelet ... MYH9-Related Disorder ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Platelet Function ... #Causes #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... #Causes #dermatology ... #physicalexam
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Mucous Membrane Disorder ... - Differential ... Diagnosis Algorithm ... lace-like) white lines ... #causes
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... mortality, and first-line ... thrombocytopenic #purpura ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology