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diagnosis hematology leukemia algorithm lymphocytic management atlas bloodcell calculation classification erythematosus gap globulin hemeonc hemolytic hodgkins index infections infectiousdiseases lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... - infiltrates (anemia ... lymphoid organs When Cancer ... Lymphadenopathy • HSM • Fevers ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Lymphadenopathy • Fevers ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... RBC: Hemoglobin SS ... myeloma Rouleaux: Chronic ... RBC #Morphology #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... bartonella (oroya fever ... Diagnosis #Algorithm #workup
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Chronic ... infiltration (e.g. cancer ... defects (e.g. sickle cell ... Production #Index #hematology ... #anemia #differential
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... ) B symptoms → fevers ... 5) Symptoms of anemia ... #Leukemia #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... hemolysis, deficiency anemia ... Malignancy: Metastatic cancer ... • Infections: Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... blood count with differential ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #oncology #management
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Immunocompromised status • Chronic ... encounters due to NTM: Chronic ... disease, alcohol, cancer ... Bone Marrow - Anemia ... NTM #Infections #differential
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