14 results
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Comparison - DRESS | SJS ... exfoliation #Febrile ... Rashes #Comparison #TABLE ... #Erythroderma #Dermatology ... #Emergency #Differential
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
skin syndrome (SSS ... Nikolsky sign, the differential ... #Diagnosis #Dermatology ... Algorithm #Nikolsky #Febrile ... #Fever #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Red Flags: • Fever ... • Extremes of age ... #dermatology #physicalexam
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... Risk factors: Age ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... Resolution > 15 days Differentials ... drug reaction • SJS ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
macule and papule (Table ... appear toxic and febrile ... have a wide differential ... pathognomonic for SJS ... #Diagnosis #Dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... organ damage • Treatment ... : - If febrile ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
< 3 months of age ... acute or subacute febrile ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... initiation • Differential ... diagnosis #management #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome Acute febrile ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology