49 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Menorrhagia • GI bleeding ... Intracranial hemorrhage Management ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Transfusion of Platelets ... procedure, no active bleeding ... 100 (rarely) Stable ... procedure - < 20 #Management ... #Platelets #Transfusion
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
• < 30,000 and bleeding ... postoperative bleeding ... Platelet transfusions ... Indications #Thresholds #Management ... #RBCs #Platelets
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... vs Acquired • Platelet ... vs Acquired #Bleeding ... Diagnosis #Algorithm #pathophysiology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... first variceal bleeding ... Prevention of variceal rebleeding ... Cirrhosis #hepatology #management
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Thrombosis and Bleeding ... Thrombosis Increased Platelet-Vesset ... #Thrombosis #Bleeding ... Clot #Cirrhosis #Pathophysiology
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... Volume #Hematology #Management ... #Table
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Circulation Platelets ... in Cirrhosis Bleeding ... Gastroenterology #diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... protein C and S Pathophysiology ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... causes #treatment #management
Treatment of Bleeding in Selected Inherited Disorders of Hemostasis

#Bleeding #Disorders #HemophiliaA #HemophiliaB #Management #Table #Treatment
Treatment of Bleeding ... Hemostasis #Bleeding ... #HemophiliaB #Management ... #Table #Treatment