38 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Mild Acne Treatment - Comedones (black/whiteheads), +/- few pustules 
1. Benzoyl Peroxide (BP) 
2. Topical Retinoid
Mild Acne Treatment ... few pustules 1. ... First line pharmacologic ... #Management #Comedones ... #Pharmacology #
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV)

Diagnosis of HUV
1) Chronic urticaria 
2) Leukocytoclastic vasculitis 
3)
Diagnosis and Management ... Diagnosis of HUV 1) ... anti-IgE, anti-IL ... -1 Dr. ... #Rheumatology
Croup Management - Epinephrine Dosing
Use steroids appropriately, as needed
In older children with mild symptoms, may consider
Croup Management ... children with mild ... 2 puffs < 1 ... SarahFoohey #Croup #Management ... Epinephrine #dosing #pharmacology
Stress Ulcer Prophylaxis

Stress ulcerations are common in ICU patients and may lead to hemorrhage if not
Critically ill patients ... hospitalization) • Pathophysiology ... Presentation • Management ... #criticalcare #pharmacology ... #management
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Levophed, alpha-1 ... dilation • beta /mild ... Vasopressors #Inotropes #Pharmacology ... #Summary #management
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
eliminate about 1/ ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management
Adult Vancomycin Guidelines
The information below provides general dosing guidelines for vancomycin. A maintenance regimen of 15-20
AUC: MIC ratio.1 ... complex critically ill ... #Management #Pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL ... -1 and IL-6, leading ... Increased soluble IL ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology