51 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Mild Acne Treatment - Comedones (black/whiteheads), +/- few pustules 
1. Benzoyl Peroxide (BP) 
2. Topical Retinoid
Mild Acne Treatment ... few pustules 1. ... First line pharmacologic ... #Management #Comedones ... #Pharmacology #
Management of Necrotizing Pancreatitis

Severe Pancreatitis
Pathophysiology
Diagnosis of Pancreatic Necrosis
Infected Necrosis
Complications of Severe Pancreatitis: 
1) Pancreatic Fistula
2) Disconnected
Management of Necrotizing ... Pancreatitis Pathophysiology ... Pancreatitis: 1) ... Pancreatic Duct Syndrome ... #Pancreatitis #Management
Hepatopulmonary Syndrome
HPS - Diagnosis:
 1. Patients with liver disease
 2. Alveolar-arterial oxygen gradient (AaP02) >15 mmHg
Hepatopulmonary Syndrome ... - Diagnosis: 1. ... Classification - Stages: • Mild ... Hepatopulmonary #Syndrome ... #diagnosis #management
Algorithm for Suspected SVC Syndrome

SVC syndrome suspected: Facial/arm/neck edema, distended neck/chest veins, facial plethora, dyspnea, cough,
SVC syndrome ... Asymptomatic 1 ... : Mild: edema of ... impairment 3: Severe: mild ... Algorithm #diagnosis #management
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Anti-IL6 Agents ... in COVID19 IL ... Cytokine Activation Syndrome ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Lamotrigine • Mild ... Stevens-Johnson Syndrome ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Croup Management - Epinephrine Dosing
Use steroids appropriately, as needed
In older children with mild symptoms, may consider
Croup Management ... children with mild ... 2 puffs < 1 ... SarahFoohey #Croup #Management ... Epinephrine #dosing #pharmacology
Stress Ulcer Prophylaxis

Stress ulcerations are common in ICU patients and may lead to hemorrhage if not
Critically ill patients ... hospitalization) • Pathophysiology ... Presentation • Management ... #criticalcare #pharmacology ... #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... Differential #Diagnosis #Management