20 results
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Nodular pattern 1. ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... Nodular #Pattern #Comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... the critically ill ... coagulation defects. 1) ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... the critically ill ... coagulation defects. 1) ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
nodular pattern. 1. ... Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... bronchiolitis: ill ... #Differential #Comparison
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
synthesis, e.g., IL ... -1, IL-2 Muromonab-CD3 ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Lamotrigine • Mild ... alopecia (unusual), thrombocytopenia ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
• Chills • Thrombocytopenia ... PATHOPHYSIOLOGY: ... Pyrogen (TNF, IL ... -1, IFN, IL-6): ... Rigors #Bacteremia #Pathophysiology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
cytometry — GP Ilb ... either severe Type 1 ... Gplb receptor • Thrombcytopenia ... Platelet #disorders #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL ... -1 and IL-6, leading ... leukopenia, anemia, and thrombocytopenia ... Diagnosis #Management #Hematology ... #Rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Ischemic Liver, IBD ... Heparin-induced thrombocytopenia ... Venous #Arterial #pathophysiology ... #hematology #differential