11 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Lamotrigine • Mild ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
• Persons with psychiatric ... failure to thrive • Ill ... Psychiatric symptoms ... Supplementation with 1 ... #AscorbicAcid #Pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
at > 17 years old ... than females (4:1) ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... arthritic flare. 1. ... to Manifest: 1. ... Gout #Comparison #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... • Interstitial Pneumonitis ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
Lithium Therapy for Bipolar Disorder 
Toxicity Levels: 
 - Mild (1-1.5 mEq/L) 
 - Moderate (1.6-2.5
Toxicity Levels: - Mild ... (1-1.5 mEq/L) ... BPD #Toxicity #Pharmacology ... #Psychiatry
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
is considered mild ... present in only 1 ... than females (1.4:1) ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
months, with >1 ... individual is >18 years old ... in childhood (> 1 ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry