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diagnosis management comparison differential lupus treatment hematology pulmonary ana antinuclear associations autoantibodies clinical ctchest druginduced erythematosus radiology radiologyassistant summary systemic
Nodular pattern 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary TB: random nodules 3. Sarcoidosis: nodules with perilymphatic
Nodular pattern 1. ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... Pattern #Comparison #Table
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
rheumatoid arthritis SLE ... ConnectiveTissueDiseases #ILD ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Myositis: Anti-JO-1, ... RNA Polymerase Ill ... #associations #table
On the left some diseases with a nodular pattern. 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary
nodular pattern. 1. ... Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... bronchiolitis: ill ... Differential #Comparison #Table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Anti-Jo-1 - Polymyositis ... diseases #diagnosis #table ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
drug-dependent, 4:1 ... to 1:1 F:M • Clinical ... Prognosis: Usually mild ... #comparison #table ... #rheumatology #
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome: Jo-1, ... clinical #diagnosis #rheumatology ... #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... syndromes Anti-PCNA 1- ... erythematosus #diagnosis #rheumatology ... #table #ANA
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
celiac disease, CF, IBD ... RA, SLE), Post-partum ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
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