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management sle systemic hematology activation classification comparison differential dil drugs eularacr hemeonc hemophagocytic hlh lymphohistiocytosis macrophage mas medications pharmacology risk
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria ... Erythematosus ... nephritis, Class Ill ... #Erythematosus ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... pneumonitis • ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... Erythematosus ( ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
-1 and IL-6, leading ... erythematosus ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... Erythematosus ... Lupusreference #DrugInduced ... #differential #diagnosis ... #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... erythematosus ( ... cell lymphoma Pathophysiology ... Histopathological Diagnoses ... #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Management #Hematology
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