12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... symptoms, or> 1 ... #APML #diagnosis ... #oncology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , others (RNP, aPL ... Myositis: Anti-JO-1, ... RNA Polymerase Ill ... #diagnosis #associations
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
- Differential Diagnosis ... Algorithm Idiopathic ... ), Heme malig (AML ... Viral (HIV, HTLV-1) ... IBD Stanford Internal
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... -1 and IL-6, leading ... Histopathologic criteria ... #Diagnosis #Management ... #Hematology #Rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Criteria: • Elevated ... erythropoietin 1/ ... transformation into AML ... • Treatment algorithms ... Summary #treatment #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... CLL Labs: 1. ... • Richter’s Syndrome ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... #Rheumatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... • Metabolic syndrome ... Gout #Comparison #rheumatology ... #Diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... within the first 1 ... criteria, but the ... decrease in HIV-1 ... #Inflammatory #Syndrome
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Algorithm in Cancer ... losses, CAR-T- and IL ... capillary leak syndrome ... adrenalitis; PD-1 ... #nephrology #oncology