80 results
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
pembrolizumab) -Pneumonitis ... -It’s a diagnosis ... during therapy. -1/ ... common presenting symptom ... There are case reports
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... and iron release Diagnosis ... improvement in symptoms ... endpoint of all-cause
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... - Differential Diagnosis ... this should be 1° ... Chronic Radiation Pneumonitis ... Lung #Diseases #ILD
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Onset Alzheimer's (1% ... - Presenilin 1 ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and duration of symptoms ... angioedema Other symptoms ... Cold #Urticaria #diagnosis ... #rheumatology #
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
arteritis (GCA) 1) ... Is visual loss caused ... the optic nerve caused ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... patients have no symptoms ... at the time of diagnosis ... #Sarcoidosis #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Prognosis: Usually mild ... constitutional symptoms ... comparison #table #rheumatology ... #diagnosis #management
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... hemianopsia IGF-1 ... Overproduction #diagnosis ... #signs #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage 1: ... Mild/vasoconstrictive ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms