164 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Vasculitides, IBD ... Glucocorticoids, IL ... TPO, TPO-RA • Infections ... : Chronic infections
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
pembrolizumab) -Pneumonitis ... exclusion: rule out infection ... during therapy. -1/ ... associated with a clinical ... #Clinical #Diagnosis
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Nodular pattern 1. ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... #Clinical #Radiology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
Mild infection: ... Mild infection: ... erysipelas with no focus ... oral antibiotic treatment ... or those with clinical
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
nodular pattern. 1. ... Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... bronchiolitis: ill ... #Clinical #Diagnosis
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
Non-HCV infectious ... cryoglobulinemia vasculitis Clinical ... neuropathy Treatment ... Specific anti-infectious ... Cryoglobulinemia #Vasculitis #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... #summary #rheumatology
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
other interstitial pneumonias ... Organizing Pneumonia - Clinical ... Hypersensitivity pneumonitis ... Organizing Pneumonia Treatment ... BOOP #pulmonary #ILD
Telescoping Fingers on Physical Exam

A 69-year-old woman with rheumatoid arthritis presented for the treatment of severe
Exam A 69-year-old ... presented for the treatment ... RheumatoidArthritis #Clinical ... #Video #Rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... Inflammatory: • IBD ... effect following treatment ... Algorithm #Causes #Hematology