10 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... -1 and IL-6, leading ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... symptoms, or> 1 ... APML #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... respiratory distress syndrome ... including: 1. ... Exclusion of other ILDs ... #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... and lower jaw Treatment ... -1 inhibitors, IL ... #Rheumatology # ... diagnosis #management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... features: 1. ... filling +++ (risk of pulmonary ... #diagnosis #management ... #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... within the first 1 ... decrease in HIV-1 ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... • Interstitial Pneumonitis ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... dysfunction. 1. ... hyperinflammatory syndrome ... Treatment Approach ... #Hematology #HemeOnc
Unilateral Floppy Eyelid Syndrome

This middle-aged male reported to clinic for persistent blurry vision and irritation of
Floppy Eyelid Syndrome ... mentioned that his lid ... Our management for ... PhysicalExam #clinical #video ... #ophthalmology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
disease states 1. ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology ... #diagnosis #management