16 results
hematology management abnormal ana antinuclear causes coagulation cytoplasmic joint pain prolonged pt testing activation aggregometry algorithm antinxp2 antinxp2dm arthritis autoimmune
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... SLE, SjS, CTD-ILD ... phenomenon - EJ, Jo-1, ... #differential # ... diagnosis #rheumatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... antiglobulin test, PT/aPTT ... schistocytes > 1% ... hemosiderin • PT/aPTT ... #Algorithm #hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
activity (e.g. antibody ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
) 1. ... FVIII antibody ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
On the left some diseases with a nodular pattern. 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary
with a nodular pattern ... . 1. ... Hypersensitivity pneumonitis ... #Clinical #Diagnosis ... NodularPattern #Differential
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
platelet, PT, PTT ... cytometry — GP Ilb ... either severe Type 1 ... Platelet #disorders #hematology ... #diagnosis #Aggregometry
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Causes include : 1. ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
gangrenosum • IBD ... Antiphospholipid-antibody ... Sarcoidosis #dermatology ... #skin #rashes #differential ... #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... SLE, SjS, CTD-ILD ... phenomenon • EJ, Jo-1, ... #differential # ... diagnosis #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... performed PT, PTT ... WBC count and differential ... #Workup #Hematology
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