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diagnosis lupus ana antibody antinuclear arthritis cytoplasmic druginduced joint neurology pain patterns syndrome testing treatment activation algorithm approach cardiology cardiomyopathy
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... , SjS, CTD-ILD, ... phenomenon - EJ, Jo-1, ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Lung Disease - Differential ... this should be 1° ... Chronic Radiation Pneumonitis ... Amy Chung, MD, MSc ... Lung #Diseases #ILD
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... lasting > 30 mins - 1 ... arthritis • SLE ... #Diagnosis #MSK ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as IL ... -1 and IL-6, leading ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Joints Involved 1) ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
AMA Speckled: • SLE ... , SjS, CTD-ILD, ... phenomenon • EJ, Jo-1, ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... weakness in: 1. ... life-threatening Differential ... EMG Findings: 1. ... Gravis #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
varying degrees of: 1. ... Evaluate for NMO, SLE ... Disorders: - SLE ... Myelitis #diagnosis #management ... #neurology #differential
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