174 results
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Hypersensitivity pneumonitis ... ILD caused by inhalation ... • Radiation pneumonitis ... Idiopathic Interstitial Pneumonias ... differential #pulmonary #causes
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Hypersensitivity, Pneumonitis ... BrighamChiefs #ILD ... #Causes #Differential
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
pembrolizumab) -Pneumonitis ... well as radiation pneumonitis ... There are case reports ... associated with a clinical ... #Clinical #Diagnosis
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... #Clinical #Radiology
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
other interstitial pneumonias ... Unknown • 6-7 cases ... Organizing Pneumonia - Clinical ... Hypersensitivity pneumonitis ... BOOP #pulmonary #ILD
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... bronchiolitis: ill ... #Clinical #Diagnosis
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... , worse at the bases ... Chronic Radiation Pneumonitis ... Lung #Diseases #ILD ... #Causes #Differential
Interstitial pneumonias
An acute reticular pattern is most frequently caused by interstitial edema due to cardiac heart
Interstitial pneumonias ... most frequently caused ... The other cause ... #Clinical #Radiology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH) Clinical ... activity, ↑ soluble IL ... Histiocyte Society Criteria ... the following 8 criteria ... activity • ↑ soluble IL
Aortitis - Diagnosis and Workup
Clinical History:
 - Fever, weight loss, deterioration of general health
 - Aortic
Diagnosis and Workup Clinical ... depending on the cause ... Spondyloarthritis, IBD ... #Differential #Causes