15 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... and Management ... of Sickle Cell Crises ... #Diagnosis #Management ... #Hematology #SickleCell
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
the critically ill ... child * Severe cases ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
the critically ill ... child * Severe cases ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
celiac disease, CF, IBD ... Septic shock, Obstetric ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... diagnosis: 70 years old ... , ~10,000 new cases ... acute leukemia Management ... #treatment #hematology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
of the Disease Mild ... Concern for HES: • Hematology ... consult for evaluation ... Gastroenteritis #Treatment #management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... decrease in most cases ... differential - Shows a mild ... hematuria (without casts ... Diagnosis #Workup #Hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... may be normal in mild ... cases) • PT/INR ... Chronic Management ... #treatment #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... Discontinuation of causal ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... Drugs, Unknown cause ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology