15 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the ... Evaluation and ... Cell Crises Clinical ... #Hematology #SickleCell ... Manifestations #Workup
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... during medical evaluation ... or workup for specific ... 1,500 cells/µL Workup ... Differential #diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... • Immunologic Workup ... Positive in 60-80% of cases ... of SLE • Evolution ... #Summary #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... diagnosis: 70 years old ... , ~10,000 new cases ... #treatment #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... normal, further evaluation ... including liver and hematologic ... hemochromatosis #algorithm ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
steroids • In mild ... cases associated ... Options for severe cases ... #Treatment #management ... #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Prognosis: Usually mild ... Discontinuation of causal ... • Immunologic Workup ... comparison #table #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... decrease in most cases ... hematuria (without casts ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management