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diagnosis lupus sle syndrome treatment druginduced erythematosus algorithm calcium comparison complications cppd ddxof deposition dermatology dil disease hemophagocytic hlh lymphohistiocytosis
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... and Management ... of Sickle Cell Crises ... #Hematology #SickleCell ... Manifestations #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Summary • Epidemiology ... • Immunologic Workup ... of SLE • Evolution ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... Treatment: • Mild ... Erythematosus #SLE #Summary ... #diagnosis #rheumatology ... #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... diagnosis: 70 years old ... , ~10,000 new cases ... #treatment #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Prognosis: Usually mild ... months to years) Systemic ... • Immunologic Workup ... comparison #table #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... decrease in most cases ... hematuria (without casts ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... • Interstitial Pneumonitis ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... Prognosis: Usually mild ... Discontinuation of causal ... DrugInduced #Lupus #DIL #rheumatology ... diagnosis #treatment #management
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