11 results
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Hypersensitivity pneumonitis ... ILD caused by inhalation ... Polymyositis-dermatomyositis, Lupus ... Pneumonias: • ... #causes
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Hypersensitivity, Pneumonitis ... • Treatment Related ... #Diagnosis #interstitial ... lung #disease #pulmonary
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... leaking out of pulmonary ... Arthritis, Systemic Lupus ... Chronic Radiation Pneumonitis ... Lung #Diseases #ILD
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
Unknown • 6-7 cases ... Organizing Pneumonia Treatment ... Pneumonia #COP #BOOP #pulmonary ... #ILD #diagnosis ... #management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... renal histological evaluation ... #treatment #management ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... life-threatening • Treatment ... of SLE • Evolution ... #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... pneumonitis ... Exclusion of other ILDs ... macrophages Treatment ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... Treatment: • ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Pneumonitis (LIP ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management