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management rheumatology dermatology syndrome hepatology comparison differential hemeonc hemophagocytic hlh lymphohistiocytosis summary activetb cardiology causes chronic coccidioidomycosis fever fungal gammopathy
Telescoping Fingers on Physical Exam A 69-year-old woman with rheumatoid arthritis presented for the treatment of severe
Exam A 69-year-old ... presented for the treatment ... Telescoping #Fingers #PhysicalExam ... RheumatoidArthritis #Clinical ... #Video #Rheumatology
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 Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... cytokines (TNFa,lL1, IL6 ... accumulation of clinical ... Assessment • Clinical
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... bleeding disorder Clinical ... platelet count (mild ... factor VIII) Treatment ... #Diagnosis #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... may be normal in mild ... that ↑ bleeding risk ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis
Leptospirosis Pathogen: Leptospira (interrogans, kirschneri, noguchii) Risk Factors: • Occupational exposure - Farmers, ranchers, trappers, veterinarians • Recreational
kirschneri, noguchii) Risk ... Presentation: • Mild ... ARDS Diagnosis ... Epidemiologic exposure + clinical ... #treatment #management
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
factors: Critical ... sequestration and activation ... : 33% • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... in those with CLD ... months without treatment ... underlying liver disease ... gastroenterology #management #diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... pneumonia • DM risk ... Pneumonitis 3. ... Lung Abscess - Clinical ... hemorrhage • Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... age, however the disease ... • Bicytopenia Treatment ... #hematology
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