142 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... Megaloblastic Anemia ... #Peripheral #Blood ... #Smear #Analysis
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
thought to be precursors ... Path #BloodSmear #Blood ... #Smear #BlisterCells
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... Smear. ... P. falciparum causes ... smears - don't ... #Smear.
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Diagnosis Algorithm Blood ... Normochromic RBCs on Smear ... Spherocytes on Smear ... Diagnosis #Algorithm #Causes
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... Path #BloodSmear #Blood ... #Smear #Elliptocyte
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... type ± C3d • Blood ... smear: Differential ... 2) LOOK FOR a cause
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... Path #BloodSmear #Blood ... #Smear #Dacrocytes
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... • Peripheral blood ... smear + DAT + further ... → Sickle Cell anemia ... Diagnosis #Algorithm #causes
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
Nucleated red blood ... fetus/newborn the causes ... maturation of red cell precursors ... #BloodSmear #Blood ... #Smear #Nucleated
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... Smear • Drugs ... • Pernicious Anemia ... Diagnosis #Algorithm #Causes