25 results
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
thought to be precursors ... Clinical #Path #BloodSmear ... #Blood #Smear #
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
maturation of red cell precursors ... #Path #Peds #BloodSmear ... #Blood #Smear #
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
and Associated Diseases ... Microscopy #Pathology #Hematology ... #Dyspmorphic #BloodSmear ... Pathologic Basis of Disease
Stomatocyte - The appearance of stomatocytes with their oval or rectangular central pallor has been compared
seen in liver disease ... Clinical #Path #BloodSmear ... #Blood #Smear #
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... cells: Sickle cell disease ... Peripheral #Blood #Smear ... #Analysis #hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... formation #Clinical #Smear ... #Hematology #Pathology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... • Nonmalignant hematologic ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Normochromic RBCs on Smear ... Anemia of Chronic Disease ... Spherocytes on Smear ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
peripheral blood smear ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... dysplasia on the smear ... Causes #Workup #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
, Drugs, Liver Disease ... Electrolytes: Wilson's disease ... Peripheral Blood Smear ... Differential #Diagnosis #hematology