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diagnosis hematology anticoagulation aptt differential ptt causes doac laboratory management prolonged thrombin warfarin anatomy apaxiban apixaban bleeding bruising cascade chemistry
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... and anticoagulants ... #coumadin #heparin ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... on Coagulation ... Tests PT / INR, ... Clotting Time, Thrombin ... EricsMedicalLectures/ #Anticoagulants
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... inhibitor and lupus anticoagulant ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
to Evaluate an Abnormal ... Step 1: Is the PT ... Patient Receiving Anticoagulants ... K Antagonists, Heparin ... , or Direct Thrombin
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... at the site of injury ... #clot #PT #PTT ... anticoagulation #anticoagulant ... Rivaroxaban #Edoxaban #heparin
Paracentesis Anatomy Landmarks Don't hit the inferior epigastric artery!!! Go 2cm below the umbilicus in the midline
in the setting ... cirrhosis, despite abnormal ... tests of coagulation ... Prolonged PT) because ... procoagulants and anticoagulants
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... - Other anticoagulants ... drugs e.g. direct thrombin ... Jcortesizaguirr #Abnormal
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... 100mg/dL) - Heparin
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... within and above typical ... assay; ECT = ecarin ... clotting time; TT = thrombin ... hematology #laboratory #testing
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
AST/ALT > ALP: Typical ... - If both are normal ... • Albumin • Coagulation ... factors: PT/INR ... replaced by non-hepatic
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