9 results
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... Coagulation Tests PT ... Clotting Time, Thrombin ... EricsMedicalLectures/ #Anticoagulants ... #Diagnosis #Laboratory
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Patient Receiving Anticoagulants ... K Antagonists, Heparin ... , or Direct Thrombin ... APTT #prolonged #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... inhibitor and lupus anticoagulant ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... deficiency • Anticoagulant
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant ... Rivaroxaban #Edoxaban #heparin
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... - Other anticoagulants ... drugs e.g. direct thrombin ... Jcortesizaguirr #Abnormal ... #Causes #diagnosis
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Pt had extensive ... Started on heparin ... 3 d later with normal ... Echocardiogram #A4C
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... within and above typical ... assay; ECT = ecarin ... clotting time; TT = thrombin ... hematology #laboratory #testing
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
AST/ALT > ALP: Typical ... - If both are normal ... Coagulation factors: PT ... replaced by non-hepatic ... liver #chemistry #diagnosis