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diagnosis hematology coagulation anticoagulation aptt differential doac ptt abnormal anticoagulants apixaban cascade causes dabigatran laboratory noac pathophysiology pharmacology prolonged rivaroxaban
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade and anticoagulants ... coagulation #coumadin #heparin ... #warfarin #apaxiban ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... or a new oral anticoagulant ... the function of thrombin ... only, and not thrombin ... DOAC #Dabigatran #Apixaban
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... Coagulation Tests PT ... Clotting Time, Thrombin ... Time, Ecarin Clotting ... Rivaroxaban Apixaban
Coagulation Cascade - Actions of Anticoagulants • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin • Fondaparinux • Direct
Cascade - Actions of Anticoagulants ... • Heparin: Unfractionated ... heparin, Enoxaparin ... : Rivaroxaban, Apixaban ... Warfarin • Direct Thrombin
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... #clot #PT #PTT ... anticoagulation #anticoagulant ... #inhibitor #Apixaban ... Rivaroxaban #Edoxaban #heparin
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Patient Receiving Anticoagulants ... K Antagonists, Heparin ... , or Direct Thrombin ... Prolonging the PT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... unfractionated heparin ... - Other anticoagulants ... drugs e.g. direct thrombin ... inhibitors, heparin
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... Started on heparin ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Acquired: • Heparin ... syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... warfarin, direct thrombin ... deficiency • Anticoagulant
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... 100mg/dL) - Heparin
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