15 results
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade and anticoagulants ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Patient Receiving Anticoagulants ... Heparin, or Direct Thrombin ... Prolonging the PT ... mixing #studies #PTT
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... Coagulation Tests PT ... / INR, aPTT, Anti-Xa ... Clotting Time, Thrombin ... EricsMedicalLectures/ #Anticoagulants
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
== NORMAL PT ... level NORMAL PT ... If the PT remains ... DIC ABNORMAL PT ... warfarin, direct thrombin
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... FVa to generate thrombin ... Thrombin, then primes ... #clot #PT #PTT ... anticoagulation #anticoagulant
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... heparin - Other anticoagulants ... typically prolong PT ... drugs e.g. direct thrombin
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... Reduction of pro/anticoagulants
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... bilateral PTE. ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
Amyloidosis on POCUS Echocardiogram - Apical 4 Chamber (A4C)
Pt with systemic AL amyloidosis presents with 1
Echocardiogram - Apical ... 4 Chamber (A4C) ... Pt with systemic ... Pt has biventricular ... Echocardiogram #Cardiology #A4C
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
is normal and pt ... Echocardiogram #A4C ... Pulmonary #Embolism #Thrombus