8 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... at the site of injury ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... on Coagulation ... Tests PT / INR, ... Clotting Time, Thrombin ... Anticoagulation #Testing #Diagnosis
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... platelet aggregation PT ... using INR use PT ... to form clots, ... ISTH #Scoring #diagnosis
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... #Clots #InTransit
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... significant fibrin clot ... Reduction of pro/anticoagulants ... #diagnosis #causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... intravascular coagulation ... warfarin, direct thrombin ... #Differential #Diagnosis
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
heparin - Other anticoagulants ... Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... Prolonged #Causes #diagnosis
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
- Differential Diagnosis ... Algorithm Blood ... Retained blood clots ... or percreta) Thrombin ... #Algorithm #Causes