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hematology causes coagulation abnormal acute anticoagulation apixaban aptt bleeding bruising cascade clinical clot dabigatran dic disseminated echocardiogram edoxaban hemorrhage hemostasis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... #Clots #InTransit
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 Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
Diagnostic Schema ... least common): Thrombus ... Arterial - Thrombus ... inflammation → clot ... #Diagnosis #algorithm
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Diagnosis Algorithm ... 12-13 g/dL, • ANC ... iron studies, PT ... Diagnosis: • ... #Diagnosis #Algorithm
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... warfarin, direct thrombin ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Diagnosis Hepatocellular ... : Shock Liver, Thrombus ... #Acute #algorithm
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... heparin - Other anticoagulants ... drugs e.g. direct thrombin ... Prolonged #Causes #diagnosis ... #differential #
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Post-Partum Hemorrhage - Differential ... Diagnosis Algorithm ... Retained blood clots ... or percreta) Thrombin ... #Diagnosis #Algorithm
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... significant fibrin clot ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
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