20 results
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... platelet aggregation PT ... consumption of coagulation ... using INR use PT ... Intravascular #Coagulation
Pericardial Clot on Echocardiogram

ST elevation of acute pericarditis was misdiagnosed as STEMI and thrombolysed with SK
Pericardial Clot ... developed hemorrhagic pericardial ... DrRajeshG1 #Pericardial ... effusion #clot #thrombus ... clinical #cardiology #a4c
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... Thrombin, then primes ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Anticoagulants on Coagulation ... Tests PT / INR, ... Clotting Time, Thrombin
A4C. Large thrombus in pericardial fluid following Ao dissection - Cara Mercer
@cara_mercer

#Clinical #POCUS #Echocardiogram #A4C #Pericardial
A4C. ... Large thrombus in ... pericardial fluid ... Echocardiogram #A4C ... #Pericardial #Thrombus
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... • Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Schistocytes, helmet cells
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... differential #hematology #coagulation
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... drugs (e.g. direct thrombin ... #Abnormal #PT ... differential #hematology #coagulation