15 results
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... platelet aggregation PT ... consumption of coagulation ... using INR use PT ... Scoring #diagnosis #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT ... diagnosis #models #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Schistocytes, helmet cells ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... #differential #hematology ... #coagulation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Paradoxical Embolism • Cardiac ... : - Atrial thrombus ... valves - Infected cardiac ... intravascular coagulation ... pathophysiology #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... drugs (e.g. direct thrombin ... #differential #hematology ... #coagulation
Amyloidosis on POCUS Echocardiogram - Apical 4 Chamber (A4C)
Pt with systemic AL amyloidosis presents with 1
Apical 4 Chamber (A4C ... ) Pt with systemic ... Pt has biventricular ... Has new large pericardial ... #Amyloidosis #Cardiac
Hemorrhagic Pericardial Effusion with Tamponade on POCUS

In an unstable pt w/ chest trauma, subxiphoid view FIRST!

-
Hemorrhagic Pericardial ... In an unstable pt ... #Hemorrhagic #Pericardial ... Effusion #Tamponade #Cardiac ... cardiology #clinical #s4c
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... == NORMAL PT ... intravascular coagulation ... warfarin, direct thrombin ... Differential #Diagnosis #Hematology
Amyloidosis on POCUS Echocardiogram - Subcostal 4 Chamber (S4C)
Pt with systemic AL amyloidosis presents with 1
) Pt with systemic ... Pt has biventricular ... Has new large pericardial ... amyloidosis with cardiac ... #Amyloidosis #Cardiac