7 results
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... (DIC) Platelet ... platelet aggregation PT ... using INR use PT ... small vessels #DIC
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
(DIC) Overview ... • Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Schistocytes, helmet cells
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... Thrombin, then primes ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... (DIC) c. ... differential #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... drugs (e.g. direct thrombin ... intravascularcoagulation (DIC ... differential #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... Warfarin • Acute DIC ... intravascular coagulation ... disease • Acute DIC ... warfarin, direct thrombin
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View

Young Lupus patient admitted to hospital new onset HFpEF.
Also has pericardial ... effusion/pericardial ... one month ago-pt ... Did have tap next ... clinical #cardiology #s4C