13 results
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... heparin #warfarin #apaxiban ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Anticoagulants on Coagulation ... Tests PT / INR, ... aPTT, Anti-Xa Activity ... Clotting Time, Thrombin ... Rivaroxaban Apixaban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT ... #inhibitor #Apixaban
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... - Rivaroxaban, apixaban ... typically prolong PT ... drugs e.g. direct thrombin
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... Schistocytes, helmet cells
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... bilateral PTE. ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View

Young Lupus patient admitted to hospital new onset HFpEF.
you see on this SC ... Also has pericardial ... effusion/pericardial ... one month ago-pt ... clinical #cardiology #s4C
Hemorrhagic Pericardial Effusion with Tamponade on POCUS

In an unstable pt w/ chest trauma, subxiphoid view FIRST!

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Hemorrhagic Pericardial ... In an unstable pt ... #Hemorrhagic #Pericardial ... cardiology #clinical #s4c
Amyloidosis on POCUS Echocardiogram - Subcostal 4 Chamber (S4C)
Pt with systemic AL amyloidosis presents with 1
Subcostal 4 Chamber (S4C ... ) Pt with systemic ... Pt has biventricular ... Has new large pericardial ... Echocardiogram #Cardiology #S4C
Amyloidosis on POCUS Echocardiogram - Apical 4 Chamber (A4C)
Pt with systemic AL amyloidosis presents with 1
Apical 4 Chamber (A4C ... ) Pt with systemic ... Pt has biventricular ... Has new large pericardial ... Echocardiogram #Cardiology #A4C