9 results
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
(DIC) Platelet ... platelet aggregation PT ... using INR use PT ... small vessels #DIC ... Scoring #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Schistocytes, helmet cells ... treatment #management #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT ... diagnosis #models #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
drugs e.g. direct thrombin ... intravascular coagulation ... (DIC) c. ... #differential #hematology ... #coagulation
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View

Young Lupus patient admitted to hospital new onset HFpEF.
Also has pericardial ... effusion/pericardial ... one month ago-pt ... Did have tap next ... clinical #cardiology #s4C
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... drugs (e.g. direct thrombin ... intravascularcoagulation (DIC ... #differential #hematology ... #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... Warfarin • Acute DIC ... disease • Acute DIC ... warfarin, direct thrombin ... Differential #Diagnosis #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... potassium from lysed cells ... RBCs (stored at 4C ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... potassium from lysed cells ... RBCs (stored at 4C ... diagnosis #management #hematology