30 results
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
== NORMAL PT ... • Factor VIII level ... If the PT remains ... DIC ABNORMAL PT ... warfarin, direct thrombin
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... Early liver disease ... drugs e.g. direct thrombin ... Reduced liver synthesis
Step by Step Algorithmic Approach to Pediatric Fever

Age < 21 days old (or 28 days for
Approach to Pediatric Fever ... mL CRP mg/L or ANC ... Peds #Diagnosis #Management ... Algorithm #Infant #Fever
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... drugs (e.g. direct thrombin ... • Reduced liver ... #Abnormal #PT
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
is normal and pt ... What's your management ... Echocardiogram #A4C ... Pulmonary #Embolism #Thrombus
Neutropenic Fever Management Algorithm

Temperature > 38°C and ANC < 500/µL

#Neutropenic #Fever #neutropenia #oncology #Management #Algorithm
Neutropenic Fever ... Management Algorithm ... Temperature > 38°C and ANC ... #Neutropenic #Fever ... neutropenia #oncology #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... causes #treatment #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Hypofibrinogenemia • ↑ PT ... Syndrome #Diagnosis #Management
Diabetic Myonecrosis (Diabetic Muscle Infarction)
 • Spontaneous ischemic necrosis of skeletal muscle (anterior thigh or calf)
Suspect in diabetic pt ... pain • Mean AIC ... Infarction #diagnosis #management