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hematology coagulation differential prolonged ptt apixaban bleeding bruising cascade clinical clot clots dabigatran dic disseminated echocardiogram edoxaban evaluation hemostasis heparin
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
the PT or APTT ... Patient Receiving Anticoagulants ... Heparin, or Direct Thrombin ... to identify the cause ... #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... Congenital intrinsic ... #PT #aPTT #Prolonged ... #Causes #diagnosis
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... 3 d later with normal ... Echocardiogram #A4C
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... discern these causes
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and the aPTT ... affected in the intrinsic ... drugs (e.g. direct thrombin ... #PT #aPTT #Prolonged ... #Causes #diagnosis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... #clot #PT #PTT ... #diagnosis #models ... pathophysiology #anticoagulation ... #anticoagulant
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
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