8 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Prolonged? ... Heparin, or Direct Thrombin ... Prolonging the PT ... #prolonged #diagnosis
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
and/or aPTT Prolonged ... Congenital intrinsic ... PT and aPTT 1. ... #aPTT #Prolonged ... #Causes #diagnosis
Coagulation Cascade Mnemonic - PITT vs PET
PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... (with an I) = Intrinsic ... = APTT Factors ... E)= Extrinsic=PT ... Mnemonic #PITT #PET #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... aPTT are both prolonged ... affected in the intrinsic ... drugs (e.g. direct thrombin ... #aPTT #Prolonged
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... along with FXIIa (intrinsic ... #Coagulation #Cascade ... #clot #PT #PTT ... #diagnosis #models
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... #Clots #InTransit
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... integrity Clotting cascade ... prolonged after ... pathway to the intrinsic ... warfarin, direct thrombin
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... • Increased thrombin ... Fibrinogen: ↓ • PT ... #Coagulation #diagnosis