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How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... the PT or APTT ... Heparin, or Direct Thrombin ... #APTT #prolonged ... #diagnosis #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PT (INR), Prolonged ... PT (INR), Normal ... PTT, Normal PT ... PTT, Normal PT ... Differential #Diagnosis
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Congenital intrinsic ... PT and aPTT 1. ... #PT #aPTT #Prolonged ... #differential #
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and aPTT If ... aPTT are both prolonged ... affected in the intrinsic ... #PT #aPTT #Prolonged
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
pt not in distress ... Echocardiogram #A4C ... Sign #Pulmonary #Embolism ... #Thrombus #Clots ... #InTransit
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... 3 d later with normal ... Echocardiogram #A4C
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... prolonged after ... PT/ABNORMAL PTT
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... • Increased thrombin ... Fibrinogen: ↓ • PT ... #Coagulation #diagnosis
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
Segment Elevation - Differential ... Diagnosis Framework ... inversion and a prolonged ... complex Pulmonary Embolism ... #diagnosis #cardiology