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differential management hiv syndrome infections infectiousdiseases algorithm barre cns cord cytomegalovirus disorders guillain guillainbarre immune inflammatory iris lung myelitis myoclonus
Demyelinating Diseases - Differential Diagnosis • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE •
Demyelinating Diseases ... Inflammatory: MS ... • Infectious: HIV ... #Diagnosis #causes ... #neurology
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
) in HIV-AIDS Patients ... 50 or less: • Neurologic ... Retinitis (Most common cause ... Pancreatitis • Pulmonary ... #HIV #AIDS #diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
/ AIDS - Differential ... CD4 < 100 • Demyelinating ... disease caused ... - Generally >3 cm ... #AIDS #opportunistic
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Epidemiology: • 1-2 cases ... , CMV, EBV - Influenza ... polyneuropathy with demyelination ... management #treatment #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... system (CNS): demyelinating ... : • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... phenomenon (16%) MSK
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
- Differential Diagnosis ... Framework Disease ... Coccidioidomycosis, CMV ... factor • May cause ... #AIDS #pulmonary
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Infectious causes ... Etiologies: • Demyelination ... , Hep A/B/CMV, TB ... #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Non-compressive Spinal Cord Causes ... Demyelinating: ... , CMV, HTLV - ... Sarcoidosis, Behcet disease ... #neurology #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
/AIDS patients ... worsening of that disease ... be present: • AIDS ... pericarditis, peritoneal disease ... keratitis, iritis • CMV
Causes of Myoclonus - Differential Diagnosis LOCALIZATION: • Cortical: Focal/multifocal: Distal UL+ Face, Action/sensitive induced • Sub-Cortical:
Causes of Myoclonus ... Inflammatory (MS ... Chronic: Storage disease ... hepatic, septic, pulmonary ... #Causes #neurology
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