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Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Petechiae, Palpable ... purpura (16%) ... • Petechiae • Palpable
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... Viral replication causes ... endothelial cells - Palpable ... or necrotic purpura
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Arthralgia - Purpura ... Cryoglobulins Cause ... Syndrome: • Clinical ... triad of Palpable
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... Treat primary cause
Algorithm for Diagnosis of the Petechial / Purpuric Rash Febrile/Toxic, Palpable: - Meningococcaemia, Disseminated Gonococcal Infection,
the Petechial / Purpuric ... Febrile/Toxic, Palpable ... Febrile/Toxic, Non-palpable ... Afebrile/Non-Toxic, Palpable ... Non-Toxic, Non-palpable
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... Diagnosis Non-PalpabIe ... → Palpable • ... BrighamChiefs #Purpura ... #Causes #Differential
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Petechial/Purpuric ... the etiology of palpable ... Palpable (raised ... the lesions are palpable ... patients with palpable
An Approach to the Unknown Rash: Petechial-Purpuric Rash #Diagnosis #Dermatology #Petechial #Purpura #Purpuric #Rash #Palpable #Algorithm
Rash: Petechial-Purpuric ... Dermatology #Petechial #Purpura ... #Purpuric #Rash ... #Palpable #Algorithm
Causes of Purpura - Differential Diagnosis Disruption in Vascular Integrity: • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... C), Pigmented purpuric ... BrighamChiefs #Purpura ... #nonpalpable #palpable ... #Causes #Differential
Palpable Purpura - Rash Algorithm #Diagnosis #Dermatology #Rash #Palpable #Purpura #Differential #Algorithm
Palpable Purpura ... Dermatology #Rash #Palpable ... #Purpura #Differential
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