25 results
Henoch Schonlein Purpura 
Typically a young boy. Often occurs following upper respiratory tract infection. A systemic
Henoch Schonlein Purpura ... Henoch #Schonlein #Purpura ... Diagnosis #Peds #Pediatrics ... #Signs #Symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... • Progressive symptoms ... capillaritis, palpable ... (red macules, palpable ... Vasculitis) • Palpable
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Palpable Purpura ... Henoch Schonlein Purpura ... on tuberculosis treatment ... knees/ankles and palpable ... #Purpura #Henoch
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
endothelial cells - Palpable ... or necrotic purpura ... Diagnosis #Signs #Symptoms
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Henoch-Schönlein Purpura ... - Symmetric palpable ... purpura mainly ... Rheumatology #Peds #Pediatrics
Pneumocystis jirovecii Pneumonia 
Clinical 
 • Caused by Pneumocystis jirovecii (formerly carinil) 
 • Immunocompromised host
CD4 < 200 • Symptoms ... desaturation common with ambulation ... often elevated Treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
growth AND • JAK2 mutation ... When present, symptoms ... • "Vasomotor" symptoms ... • Treatment is ... the reduction of symptoms
Acute limb ischemia (ALI)

Rapid decrease in lower limb blood flow due to acute occlusion of peripheral
The symptoms of ... and irreversible purpura ... #endovascular #treatment ... #CLI #heparin #amputation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... + Bleeding Treatment ... diagnosis #causes #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Presentation - Systemic Symptoms ... scleritis • Palpable ... Skin -> causing palpable ... purpura.