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management rheumatology dermatology syndrome neurology hematology vasculitis causes skinrash cutaneous infectiousdiseases rash activetb classification hand hemophagocytic hlh latenttb lymphohistiocytosis nephrology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
cryoglobulinemia vasculitis - Diagnosis ... cryoglobulinemia vasculitis Clinical ... involvement with purpura ... neuropathy Treatment ... with refractory disease
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... Infectious: Mycoplasma ... • Ocular: uveitis ... #treatment #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... Diagnosis: Vasculitis ... cell arteritis Infections ... • Fungal infections
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
Landscaper w/ painless nodular ... wax and wane; diagnosis ... biopsy preferred Differential ... Diseases Fellowship ... #clinical #photo
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Vasculitis Differential ... Diagnosis: • Systemic ... to exclude are infections
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Diagnosis Framework ... Syndrome: - Ocular ... Differential ... to exclude are infections
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Diagnosis Framework ... related vasculitis, infections ... Petechiae, Palpable purpura ... Vasculitis: • Behcet Disease ... #diagnosis
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... Connective tissue disease ... vasculitis (3%) • Infections ... signs #lesions #diagnosis ... #clinical #manifestations
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... lesions, palpable purpura ... Behcet syndrome (Clinical ... ) Differential Diagnosis ... Arthritis, AS Treatment
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