43 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... Care TRICC - NEJM ... unnecessary and cause ... /vmoitra) #EBM
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
rapidly evolving rash ... marine microbiota & causes ... , hypotension, rash ... immunosuppressive meds ... dermatology #legs #clinical
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... with or without treatment ... , but without treatment ... resembling rashes caused ... #Diagnosis #Clinical
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
acid lipase is critical ... and gut, which causes ... #clincial #peds ... calcifications #infant #NEJM
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... Coxsackie, CMV, EBV ... diagnosis #management #treatment
Decompression Sickness - The physical examination revealed diffuse violaceous skin mottling over his trunk and arms
extent of the nausea ... #Clinical #Derm ... #EM #Radiology # ... Pneumatosis #CT #NEJM
Macroglossia in Light-Chain Amyloidosis- Physical examination revealed macroglossia, with indentations from the teeth (Panel A)...A biopsy
well-recognized cause ... diagnosis and treatment ... are critical to ... #amyloidosis #clinical ... AL #lightchain #NEJM
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment