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diagnosis acute aki algorithm hematology injury kidney nephrology agglutinin anemia autoimmune bruising classification cold dermatologic dermatology disease erythematosus gpa granulomatosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Abdominal Compartment Syndrome ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... , C3/C4, Other ... Diagnosis #nephrology #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... mucositis - Rash ... #rheumatology #
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
osmolarity If cause ... Glomerulonephritis / Vasculits ... ANCA, ANA, Anti-GBM ... Anti-ds-DNA, C3/C4 ... • Cardio-renal syndrome
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... reticularis Differential ... • Goodpasture syndrome ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... , mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM ... Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... • Mesenteric vasculitis ... Erythematosus #Diagnosis #Rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
chemotherapy) • Genetic syndromes ... EBV. CMV. ... ICL #diagnosis #hematology ... #Differential # ... Causes #lymphocytopenia
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... infections - Vasculitis ... Purpura #Bruising #Causes ... #peds #pediatrics ... #diagnosis #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... hemolysis • C3↓ C4 ... - Mycoplasma, EBV ... younger pts) Differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Symptoms: • Gottron rash ... • ANA < 20 % IBM ... statins - probably caused ... #differential #
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